Table 2 Glia to neuron ratio (GNR) in various brain regions associated with oxidative stress-related CNS disorders

Cortex (monkey)

1:1

[108]

Female bias: AD, MD, ANX

Male bias: PD, SZ, ASD

[109,110,111,112,113,114]

Cortex (human)

4:1

[115]

Cortex (rat)

1:1

[116]

Striatum (mouse)

1:17

[117]

Female bias: MD

[110, 111, 113]

Male bias: PD, SZ, ASD

Basal ganglia (human)

1:2

[118]

Female bias: MD,

[110, 111, 113, 114]

Male bias: PD, SZ, ASD

Substantia nigra pars compacta (mouse)

1:9

[119]

Female bias:—

[110, 120]

Male bias: PD, SZ

Thalamus (human)

17:1

[121]

Female bias: MD

[111, 113, 122]

Male bias: PD, SZ

Hippocampus overall (mouse)

1:1

[117]

Female bias: AD, MD, ANX,

Male bias: PD, SZ, ASD

[109,110,111,112,113,114]

CA1 (mouse)

1:2

[117]

CA3 (mouse)

1:3

[117]

Locus coeruleus (human)

27:1

[123]

Female bias: AD, MD

[110,111,112, 124, 125]

Male bias: PD, ANX

Amygdala basolateral (rat)

1:7

[117, 126]

Female bias: AD, MD, ANX,

[110, 112, 114, 127]

Male bias: PD, ASD

Spinal cord (rat)

1:6

[128]

Female bias:—

[110]

Male bias: PD

Cerebellum (mouse)

Cerebellum (human)

1:1

1:4

[117]

[115]

Female bias:—

[110, 114]

Male bias: PD, ASD