Fig. 6From: Sex-specific association between the gut microbiome and high-fat diet-induced metabolic disorders in micePICRUSt analysis predicted functional composition differences between male and female mice. The predicted metabolic functions of the gut microbiota of male and female mice given either a chow diet (CD) (a) or high-fat diet (HFD) (b) in level 2 KEGG pathways were generated. Differential enrichment analysis for KEGG level 3 pathways was performed in male and female mice fed a CD (d) or HFD (e). The sex differences in level 2 (c) and level 3 (f) KEGG microbial function pathways were also compared between the HFD groups pretreated with antibioticsBack to article page