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Table 2 Patient demographics for men and women with stroke: n = 32 women, n = 43 men. Women were significantly older at the time of stroke as compared to men, p = 0.016. There was no significant difference in premorbid conditions including Hypertension, Hyperlipidemia, Type 2 Diabetes Mellitus, Atrial fibrillation, or Smoking in men vs. women with stroke. Men had significantly higher heart disease history as compared to women, p = 0.036 in our patient population. Women had significantly worse outcomes as compared to men, in terms of discharge NIHSS, p = 0.032, and change in mRS, p = 0.009

From: Increased P450 aromatase levels in post-menopausal women after acute ischemic stroke

Stroke category and outcomes

Men (n = 43)

Women (n = 32)

p value

Age (mean ± SD)

72.8 ± 10

79.2 ± 10.4

0.016

Hypertension, n (%)

33 (76.7%)

24 (75.0%)

0.861

Hyperlipidemia, n (%)

29 (67.4%)

17 (53.1%)

0.208

Heart disease, n (%)

21 (48.8%)

8 (25.0%)

0.036

Type 2 diabetes mellitus, n (%)

12 (27.9%)

11 (34.4%)

0.548

Atrial fibrillation, n (%)

11 (25.6%)

12 (37.5%)

0.268

Smoking, n (%)

11 (25.6%)

3 (9.4%)

0.132

NIHSS on admission, median (IQR)

7(12)

13(18)

0.144

NIHSS at discharge, median (IQR)

2(3)

3(9)

0.032

Cardioembolic, n (%)

21 (48.8%)

22 (68.8%)

0.085

Large artery atherosclerosis, n (%)

7 (16.3%)

4 (12.5%)

0.749

Small vessel disease, n (%)

6 (14.0%)

3 (9.4%)

0.724

Undetermined etiology, n (%)

9 (20.9%)

3 (9.4%)

0.177

Baseline modified Rankin score, median (IQR)

0 (1)

0 (3)

0.084

Change in modified Rankin score, median (IQR) [discharge mRS − premorbid mRS]

2 (3)

4 (2)

0.009

Mortality

5 (11.63%)

5 (15.63%)

0.736