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Table 2 Patient demographics for men and women with stroke: n = 32 women, n = 43 men. Women were significantly older at the time of stroke as compared to men, p = 0.016. There was no significant difference in premorbid conditions including Hypertension, Hyperlipidemia, Type 2 Diabetes Mellitus, Atrial fibrillation, or Smoking in men vs. women with stroke. Men had significantly higher heart disease history as compared to women, p = 0.036 in our patient population. Women had significantly worse outcomes as compared to men, in terms of discharge NIHSS, p = 0.032, and change in mRS, p = 0.009

From: Increased P450 aromatase levels in post-menopausal women after acute ischemic stroke

Stroke category and outcomes Men (n = 43) Women (n = 32) p value
Age (mean ± SD) 72.8 ± 10 79.2 ± 10.4 0.016
Hypertension, n (%) 33 (76.7%) 24 (75.0%) 0.861
Hyperlipidemia, n (%) 29 (67.4%) 17 (53.1%) 0.208
Heart disease, n (%) 21 (48.8%) 8 (25.0%) 0.036
Type 2 diabetes mellitus, n (%) 12 (27.9%) 11 (34.4%) 0.548
Atrial fibrillation, n (%) 11 (25.6%) 12 (37.5%) 0.268
Smoking, n (%) 11 (25.6%) 3 (9.4%) 0.132
NIHSS on admission, median (IQR) 7(12) 13(18) 0.144
NIHSS at discharge, median (IQR) 2(3) 3(9) 0.032
Cardioembolic, n (%) 21 (48.8%) 22 (68.8%) 0.085
Large artery atherosclerosis, n (%) 7 (16.3%) 4 (12.5%) 0.749
Small vessel disease, n (%) 6 (14.0%) 3 (9.4%) 0.724
Undetermined etiology, n (%) 9 (20.9%) 3 (9.4%) 0.177
Baseline modified Rankin score, median (IQR) 0 (1) 0 (3) 0.084
Change in modified Rankin score, median (IQR) [discharge mRS − premorbid mRS] 2 (3) 4 (2) 0.009
Mortality 5 (11.63%) 5 (15.63%) 0.736