Table 1 List of the proteins differentially expressed in the secretome of female and male ECs identified by LC-MS^E

 P00352

Retinal dehydrogenase 1, ALDH1A1

9/9

66.77

5.83E−09

1.80

 P52209

6-Phosphogluconate dehydrogenase decarboxylating, PGD

3/3

18.43

3.74E−06

1.39

 P55072

Transitional endoplasmic reticulum ATPase, VCP

17/17

120.47

8.45E−07

1.31

 O00469

Procollagen-lysine_2-oxoglutarate 5-dioxygenase 2, PLOD2

3/3

16.84

1.24E−05

1.58

 O60814

Histone H2B type 1-K, HIST1H2BK

3/3

21.68

1.20E−06

1.32

 P03956

Interstitial collagenase MMP1

15/15

114.51

1.41E−08

2.84

 P04083

Annexin A1, ANXA1

6/6

39.36

1.95E−06

1.25

 P07339

Cathepsin D, CTSD

3/3

18.87

6.45E−05

1.34

 P07355

Annexin A2, ANXA2

17/17

137.10

2.19E−06

1.25

 P08758

Annexin A5, ANXA5

6/6

40.18

1.08E−06

1.41

 P11021

78 kDa glucose-regulated protein, HSPA5

11/9

75.79

2.72E−06

1.20

 P14625

Endoplasmin, HSP90B1

6/5

36.50

3.11E−05

1.25

 P21810

Biglycan, BGN

13/13

86.33

2.20E−07

1.67

 P26022

Pentraxin-related protein PTX3

9/9

67.95

4.35E−06

2.32

 P27797

Calreticulin, CALR

8/8

50.99

5.28E−05

1.31

 P30101

Protein disulfide-isomerase A3, PDIA3

6/6

38.64

2.88E−05

1.32

 P34932

Heat shock 70 kDa protein 4, HSPA4

2/2

10.64

0.000344

1.20

 P62158

Calmodulin CALM3

5/5

51.14

2.62E−08

1.30

 P80723

Brain acid soluble protein 1, BASP1

2/2

11.70

2.48E−06

1.48

 Q01995

Transgelin, TAGLN

2/2

12.26

0.000132

1.39

 Q05639

Elongation factor 1-alpha 2, EEF1A2

6/2

36.12

0.002882

1.36

 Q12841

Follistatin-related protein 1, FSTL1

3/3

17.39

1.53E−05

1.26

 Q16270

Insulin-like growth factor-binding protein 7, IGFBP7

12/12

96.80

1.43E−07

1.37