Table 1 Demographic and clinical characteristics of TARGET-OS and SEER-OS cases
| Â | TARGET-OS | SEER-OS | ||||||
|---|---|---|---|---|---|---|---|---|
Total | Females | Males | X2 p value | Total | Females | Males | X2 p value | |
N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | |||
Sex | ||||||||
 Male | 50 (57.5) |  | 50 (57.5) |  | 1635 (55.6) |  | 1635 (55.6) |  |
 Female | 37 (42.5) | 37 (42.5) |  |  | 1305 (44.4) | 1305 (44.4) |  |  |
Age at diagnosis (years) | ||||||||
 0- < 10 | 10 (11.5) | 6 (16.2) | 4 (8.0) | 0.06 | 348 (11.8) | 176 (13.5) | 172 (10.5) | 0.03 |
 10- < 20 | 67 (77.0) | 30 (81.1) | 37 (74.0) |  | 1675 (57.0) | 718 (55.0) | 957 (58.5) |  |
 20- < 40 | 10 (11.5) | 1 (2.7) | 9 (18.0) |  | 917 (31.2) | 411 (31.5) | 506 (31.0) |  |
Race/ethnicity | ||||||||
 White | 47 (65.3) | 15 (46.9) | 32 (80.0) | 0.02 | 1354 (46.7) | 623 (48.3) | 731 (45.4) | 0.20 |
 Hispanic | 11 (15.3) | 9 (28.1) | 2 (5.0) |  | 857 (29.5) | 359 (27.8) | 498 (30.9) |  |
 Black | 7 (9.7) | 4 (12.5) | 3 (7.5) |  | 459 (15.8) | 211 (16.4) | 248 (15.4) |  |
 API | 7 (9.7) | 4 (12.5) | 3 (7.5) |  | 232 (8.0) | 97 (7.5) | 135 (8.4) |  |
  Missing | 15 | 5 | 10 |  | 38 | 15 | 23 |  |
TARGET year of diagnosis | ||||||||
 1997-2005 | 34 (41.0) | 12 (32.4) | 22 (47.8) | 0.18 | - | - | - |  |
 2006-2014 | 49 (59.0) | 25 (67.6) | 24 (52.2) |  | - | - | - |  |
  Missing | 4 | 0 | 4 |  |  |  |  |  |
SEER year of diagnosis | ||||||||
 2000-2005 | - | - | - |  | 849 (28.9) | 378 (29.0) | 471 (28.8) | 0.49 |
 2006-2010 | - | - | - |  | 1025 (34.9) | 468 (35.9) | 557 (34.1) |  |
 2011-2016 | - | - | - |  | 1066 (36.3) | 459 (35.2) | 607 (37.1) |  |
Primary site | ||||||||
 Upper limb | 6 (6.9) | 4 (10.8) | 2 (4.0) | 0.35 | 397 (13.5) | 166 (12.7) | 231 (14.1) | 0.04 |
 Lower limb | 79 (90.8) | 33 (89.2) | 46 (92.0) |  | 2081 (70.8) | 910 (69.7) | 1171 (71.6) |  |
 Other | 2 (2.3) | 0 (0.0) | 2 (4.0) |  | 462 (15.7) | 229 (17.6) | 233 (14.3) |  |
TARGET metastasis at diagnosis | ||||||||
 Non-metastatic | 65 (74.7) | 25 (67.6) | 40 (80.0) | 0.22 | - | - | - |  |
 Metastatic | 22 (25.3) | 12 (32.4) | 10 (20.0) |  | - | - | - |  |
SEER stage of disease | ||||||||
 Local | - | - | - |  | 969 (36.2) | 459 (38.6) | 510 (34.3) | 0.02 |
 Regional | - | - | - |  | 1136 (42.5) | 500 (42.1) | 636 (42.8) |  |
 Distant | - | - | - |  | 569 (21.3) | 229 (19.3) | 340 (22.9) |  |
  Missing |  |  |  |  | 266 | 117 | 109 |  |
Vital status | ||||||||
 Alive | 58 (68.2) | 24 (64.9) | 34 (70.8) | 0.64 | 1971 (67.0) | 921 (70.6) | 1050 (64.2) | 0.0003 |
 Deceased | 27 (31.8) | 13 (35.1) | 14 (29.2) |  | 969 (33.0) | 384 (29.4) | 585 (35.8) |  |
  Missing | 2 | 0 | 2 |  | 0 | 0 | 0 |  |