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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Sex differences in expression of immune elements emerge in children, young adults and mice with osteosarcoma

Fig. 3

Sex differences in TARGET-OS immune cell composition. a Box plots of absolute gene signature scores for 22 immune cells estimated with CIBERSORT and the LM22 gene signature between male (black) and female (red) TARGET-OS (human) and mouse-OS. b GSEA enrichment plots and FWER values for the two most significantly enriched pathways in the MSigDB immunologic gene sets. Left plot represents the running enrichment score against GSE5099_CLASSICAL_M1_VS_ALTERNATIVE_M2_MACROPHAGE_DN and right plot against GSE5099_DAY3_VS_DAY7_MCSF_TREATED_MACROPHAGE_DN

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