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Fig. 5 | Biology of Sex Differences

Fig. 5

From: Investigation of interleukin-2-mediated changes in blood pressure, fetal growth restriction, and innate immune activation in normal pregnant rats and in a preclinical rat model of preeclampsia

Fig. 5

Circulating sFlt-1 in RUPP control rats and RUPP rats treated with increasing doses of IL-2. sFlt-1 was lowered with all three doses of IL-2, but only reached significance with the MD. Sflt-1 was 47.34 ± 12 pg/ml in RUPP rats (n = 6); RUPP + LD IL-2 sFlt-1 levels were 20.82 ± 8 pg/ml (n = 6), 9.34 ± 4.37 pg/ml (p < 0.05 vs RUPP) in RUPP + MD IL-2 (n = 8), and was 27.32 ± 5 pg/ml in RUPP + HD IL-2 (n = 8). There was no change with basiliximab treatment in RUPP rats (n = 8) compared to RUPP controls

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Biology of Sex Differences

ISSN: 2042-6410

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