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Fig. 1 | Biology of Sex Differences

Fig. 1

From: Investigation of interleukin-2-mediated changes in blood pressure, fetal growth restriction, and innate immune activation in normal pregnant rats and in a preclinical rat model of preeclampsia

Fig. 1

The mean arterial pressure (MAP) for each group. MAP was elevated in RUPP (n = 9) vs. normal pregnant rats (NP) (n = 11). Low (LD) (n = 3) and high (HD) (n = 4) dose IL-2 treatment in RUPP rats decreased MAP in comparison to RUPPs. The middle (MD) (n = 4) dose of IL-2 had a similar MAP as NP rats. Basiliximab treatment had no effect on NP and RUPP MAP. RUPP + basiliximab (n = 9) treatment increased MAP in comparisons to NP and NP + basiliximab (n = 7) treatment. Statistical differences were achieved using two-way ANOVA with Bonferroni post hoc analysis, *p < 0.05 vs NP control and +p < 0.05 vs. RUPP control. Student t test was also used in comparing NP + basiliximab vs. RUPP + basiliximab, αp < 0.05 vs NP + basiliximab

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Biology of Sex Differences

ISSN: 2042-6410

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