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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Selective deletion of endothelial mineralocorticoid receptor protects from vascular dysfunction in sodium-restricted female mice

Fig. 3

Sodium restriction impairs endothelial function in female mice only in an NO-dependent manner. Endothelial-dependent relaxation responses to acetylcholine (ACH) (a), endothelial-independent relaxation responses to sodium nitroprusside (SNP) (b), and relaxation responses to acetylcholine in the presence of nitric oxide synthase inhibitor Nω-Nitro-L-arginine methyl ester hydrochloride (LNAME) (c) in male and female mice on NSD or SRD. Two-way ANOVA of dose-response curves with repeated measures (*P < 0.05, male NSD N = 5, male SRD N = 8, female NSD N = 5, female SRD N = 11)

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Biology of Sex Differences

ISSN: 2042-6410

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