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Fig. 10 | Biology of Sex Differences

Fig. 10

From: Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice

Fig. 10

Transgene expression increased spontaneous excitatory postsynaptic current (sEPSC) in both sexes. a Examples of intracellular sEPSC recordings (voltage clamped at − 60 mV). b Frequency of sEPSC was higher in neurons from 20-month-old 3xTg-AD mice for both sexes. c sEPSC amplitude was not affected by sex or transgene expression. The number of mice included in each group was 3 for NonTg males, 5 for 3xTg-AD males, 5 for NonTg females, and 4 for 3xTg-AD females. Statistical comparisons were performed using two-way ANOVA. ***p = 0.001

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Biology of Sex Differences

ISSN: 2042-6410

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