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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Acute kidney injury during pregnancy leads to increased sFlt-1 and sEng and decreased renal T regulatory cells in pregnant rats with HELLP syndrome

Fig. 3

Anti-angiogenic proteins are increased in HELLP and AKI rats. Circulating sFlt-1 (a) and sEng (b) were significantly increased in HELLP and HELLP+AKI rats compared to NP rats (n = 7–8/group). CD3+CD4+ T cells are increased in HELLP rats and in HELLP+AKI rats between indicated groups (c; n = 5/group); CD4+FOXP3+ and T regulatory (CD4+CD25+FOXP3+) cells are significantly increased between the indicated groups whereas there are no differences between in RORγ+ populations (d; n = 5/group). ****p < 0.05–p < 0.0005 between the indicated groups

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