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Fig. 1 | Biology of Sex Differences

Fig. 1

From: Acute kidney injury during pregnancy leads to increased sFlt-1 and sEng and decreased renal T regulatory cells in pregnant rats with HELLP syndrome

Fig. 1

Ischemia reperfusion (IR) during pregnancy increases hypertension and parameters of HELLP in NP rats. Mean arterial pressure was significantly increased in HELLP and HELLP+AKI rats (a). HELLP and NP rats subjected to IR had increased lactate dehydrogenase (b) and aspartate aminotransferase (c) and decreased platelet counts (d). The weight of both kidneys per animal was averaged (grams), and the ratio of kidney/body weight (grams) was determined (e) as was the average weight of pups per group (f). *****p < 0.05–p < 0.00005 between indicated groups. N = 13–15/group

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