Sex differences in brain atrophy in multiple sclerosis

Table 3 Clinical measures

Clinical measures	Female MS Mean ± SD (n)	Male MS Mean ± SD (n)	Absolute difference	Percent difference	^‡p value q value Hedge’s g
9-Hole peg test	19.6 ± 3.0 s (46)	22.3 ± 5.4 s (30)	2.7 s	13.1%	p = 0.016 q = 0.048 g =0.66
Timed 25-foot walk	4.69 ± 1.0 s (45)	4.68 ± 1.7 s (27)	− 0.01 s	− 0.1%	p = 0.98 q = 1.00 g = 0.001
Symbol digit modalities test	59.6 ± 14.7 (44)	55.8 ± 14.3 (32)	− 3.8	− 6.5%	p = 0.20 q = 0.60 g = 0.26

9-hole peg test (9HPT), timed 25-foot walk (T25FW), and symbol-digit modalities test (SDMT) from female and male MS patients. ‡ p is the uncorrected p value, q is p value adjusted for multiple comparisons using the Bonferroni correction, and g is Hedge’s g

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