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Table 1 Descriptive characteristics

From: Sex differences in brain atrophy in multiple sclerosis

Descriptive characteristics Female MS patients (n = 52) Male MS patients (n = 37) p value Female healthy controls (n = 28) Male healthy controls (n = 17) p value
Age
 Mean ± SD (years) 42.1 ± 12.4 40.7 ± 11.7 0.60 38.2 ± 12.5 37.2 ± 15.7 0.83
 Median, IQR 42.3, 31.8–50.7 40.0, 32.0–49.7   35.3, 29.7–44.0 30.5, 26.1–40.6  
 Range 18.1-66.8 20.3-64.1   20.5–69.0 21.5–68.3  
Duration of MS (from Dx)
 Mean ± SD (years) 8.5 ± 7.7 8.5 ± 6.8 1.00 n/a n/a n/a
 Median, IQR 5.9, 1.9–14.5 7.3, 2.2–13.0   n/a n/a  
 Range 0.3-28.6 0.0-23.9   n/a n/a  
EDSS
 Mean ± SD 2.4 ± 1.4 2.3 ± 1.5 1.00 n/a n/a n/a
 Median, IQR 2.0, 1.5–3.0 2.0, 1.0–3.0   n/a n/a  
 Range 0–6.5 0–6.0   n/a n/a  
T2-hyperintense (FLAIR) white matter lesion count
 Mean ± SD 33.9 ± 22.7 35.1 ± 25.4 0.83 4.4 ± 7.1 6.9 ± 12.0 0.43
 Median, IQR 35, 14.8–48 30, 17-48   2, 0–4.3 1, 0–6  
 Range 2–107 0-128   0–30 0–43  
T2-hyperintense (FLAIR) white matter lesion volume
 Mean ± SD (cc) 8.1 ± 10.8 8.1 ± 8.2 0.98 0.3 ± 0.5 1.0 ± 3.5 0.39
 Median, IQR 4.8, 1.2–10.5 5.7, 1.9–11.4   0.1, 0.0–0.2 0.0, 0.0–0.2  
 Range 0.1–50.0 0.0–31.8   0.0–2.0 0.0–14.6  
  1. Descriptive characteristics of the MS and healthy control populations