Table 1 Descriptive characteristics
From: Sex differences in brain atrophy in multiple sclerosis
Descriptive characteristics | Female MS patients (n = 52) | Male MS patients (n = 37) | p value | Female healthy controls (n = 28) | Male healthy controls (n = 17) | p value |
|---|---|---|---|---|---|---|
Age | ||||||
 Mean ± SD (years) | 42.1 ± 12.4 | 40.7 ± 11.7 | 0.60 | 38.2 ± 12.5 | 37.2 ± 15.7 | 0.83 |
 Median, IQR | 42.3, 31.8–50.7 | 40.0, 32.0–49.7 |  | 35.3, 29.7–44.0 | 30.5, 26.1–40.6 |  |
 Range | 18.1-66.8 | 20.3-64.1 |  | 20.5–69.0 | 21.5–68.3 |  |
Duration of MS (from Dx) | ||||||
 Mean ± SD (years) | 8.5 ± 7.7 | 8.5 ± 6.8 | 1.00 | n/a | n/a | n/a |
 Median, IQR | 5.9, 1.9–14.5 | 7.3, 2.2–13.0 |  | n/a | n/a |  |
 Range | 0.3-28.6 | 0.0-23.9 |  | n/a | n/a |  |
EDSS | ||||||
 Mean ± SD | 2.4 ± 1.4 | 2.3 ± 1.5 | 1.00 | n/a | n/a | n/a |
 Median, IQR | 2.0, 1.5–3.0 | 2.0, 1.0–3.0 |  | n/a | n/a |  |
 Range | 0–6.5 | 0–6.0 |  | n/a | n/a |  |
T2-hyperintense (FLAIR) white matter lesion count | ||||||
 Mean ± SD | 33.9 ± 22.7 | 35.1 ± 25.4 | 0.83 | 4.4 ± 7.1 | 6.9 ± 12.0 | 0.43 |
 Median, IQR | 35, 14.8–48 | 30, 17-48 |  | 2, 0–4.3 | 1, 0–6 |  |
 Range | 2–107 | 0-128 |  | 0–30 | 0–43 |  |
T2-hyperintense (FLAIR) white matter lesion volume | ||||||
 Mean ± SD (cc) | 8.1 ± 10.8 | 8.1 ± 8.2 | 0.98 | 0.3 ± 0.5 | 1.0 ± 3.5 | 0.39 |
 Median, IQR | 4.8, 1.2–10.5 | 5.7, 1.9–11.4 |  | 0.1, 0.0–0.2 | 0.0, 0.0–0.2 |  |
 Range | 0.1–50.0 | 0.0–31.8 |  | 0.0–2.0 | 0.0–14.6 |  |