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Fig. 1 | Biology of Sex Differences

Fig. 1

From: Hypogonadal hypertension in male Sprague-Dawley rats is renin-angiotensin system-dependent: role of endogenous androgens

Fig. 1

Weekly systolic blood pressure (BP) measurements of male Sprague-Dawley (SD) rats: intact (InT-control), bilaterally castrated (CsX), or CsX with TES therapy administered from weeks 10-15 (CsX-TRT; 1.75 mg kg−1; sc, 2x/week). Separate groups of testicular feminized male (Tfm) rats were CsX or CsX-TRT from weeks 10-15 (CsX-TRT-Tfm). Data points are means ± SEM (n = 5-10 rats per group). a, b, and c indicate that among the four experimental groups (Int-control, CsX, CsX-TRT-SD, and CsX-TRT-Tfm), mean values at each time point (5, 10, or 15 weeks) without common script are significantly different (0.0001 ≤ P ≤ 0.01). Plus sign, number sign, and asterisk for each experimental group (Int-control, CsX, CsX-TRT-SD, or CsX-TRT-Tfm), mean values over time (0, 5, 10, and 15 weeks) without common script are significantly different (0.0001 ≤ P ≤ 0.01)

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