Fig. 2
From: Pathophysiological effects of androgens on the female vascular system
Plasma endothelin-1 (P[ET-1]) concentration increases in control women but decreases in women with androgen excess-polycystic ovary syndrome (AE-PCOS) during testosterone (T) suppression with a gonadotropin releasing hormone antagonist (GnRH ant). Asterisk indicates greater baseline P[ET-1] in AE-PCOS compared to control. Dagger indicates changes in P[ET-1] during T suppression and T administration, P < 0.05. Data from Wenner et al. [40], with permission