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Table 6 Correlation of the anthropometric measurements of the fetuses from dams in Groups 1 and 3 with their placental weight and efficiency

From: An interaction between fetal sex and placental weight and efficiency predicts intrauterine growth in response to maternal protein insufficiency and gestational exposure window in a mouse model of FASD

  Correlation with placental weight Correlation with placental efficiency
R Punadjusted PBH-adjusted R Punadjusted PBH-adjusted
Males only
 Fetal body weight 0.15 0.20 0.32 0.73 < 0.001 < 0.001*
 Fetal brain-to-body weight ratio 0.05 0.65 0.74 − 0.55 < 0.001 < 0.001*
 Fetal heart-to-body weight ratio − 0.09 0.43 0.57 − 0.10 0.42 0.48
 Fetal liver-to-body weight ratio 0.25 0.036 0.09 − 0.18 0.12 0.19
 Fetal brain-to-liver weight ratio − 0.23 0.046 0.09 0.01 0.95 0.95
Females only
 Fetal body weight 0.17 0.10 0.13 0.65 < 0.001 < 0.001*
 Fetal brain-to-body weight ratio − 0.21 0.036 0.072 − 0.33 0.001 0.002*
 Fetal heart-to-body weight ratio − 0.19 0.059 0.09 − 0.06 0.54 0.62
 Fetal liver-to-body weight ratio 0.44 < 0.001 < 0.001* − 0.19 0.064 0.10
 Fetal brain-to-liver weight ratio − 0.42 < 0.001 < 0.001* 0.03 0.79 0.79
  1. Litters from all 4 treatments were combined and included in the analyses. The sample sizes were n = 9 litters for NP-MD-8, LP-MD-8, and LP-Alc-8 groups; n = 8 litters for NP-Alc-8 group. P values before and after multiple testing adjustment using Benjamini-Hochberg method are presented
  2. *Statistical significance at P < 0.05