An interaction between fetal sex and placental weight and efficiency predicts intrauterine growth in response to maternal protein insufficiency and gestational exposure window in a mouse model of FASD

Table 5 Correlation of the anthropometric measurements of the placentas and fetuses from dams in Groups 1 and 3 with their litter size

	Males only			Females only
	R	P_unadjusted	P_BH-adjusted	R	P_unadjusted	P_BH-adjusted
Placental weight	− 0.32	0.006	0.030*	− 0.27	0.008	0.040*
Placental efficiency	0.42	< 0.001	< 0.001*	0.33	< 0.001	< 0.001*
Fetal body weight	0.24	0.040	0.13	0.19	0.058	0.18
Fetal brain-to-body weight ratio	− 0.10	0.39	0.65	− 0.17	0.11	0.22
Fetal heart-to-body weight ratio	0.05	0.67	0.74	− 0.03	0.81	0.81
Fetal liver-to-body weight ratio	− 0.07	0.57	0.74	− 0.18	0.073	0.18
Fetal brain-to-liver weight ratio	0.05	0.65	0.74	0.07	0.48	0.65

Litters from all 4 treatments were combined and included in the analyses. The sample sizes were n = 9 litters for NP-MD-8, LP-MD-8, and LP-Alc-8 groups; n = 8 litters for NP-Alc-8 group. P values before and after multiple testing adjustment using Benjamini-Hochberg method are presented
*Statistical significance at P < 0.05

ISSN: 2042-6410