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Table 4 Correlation of the anthropometric measurements of the fetuses from dams in Groups 1 and 2 with their placental weight and efficiency

From: An interaction between fetal sex and placental weight and efficiency predicts intrauterine growth in response to maternal protein insufficiency and gestational exposure window in a mouse model of FASD

  Correlation with placental weight Correlation with placental efficiency
R Punadjusted PBH-adjusted R Punadjusted PBH-adjusted
Males only
 Fetal body weight 0.12 0.24 0.40 0.70 < 0.001 < 0.001*
 Fetal brain-to-body weight ratio 0.003 0.98 0.98 − 0.43 < 0.001 < 0.001*
 Fetal heart-to-body weight ratio − 0.01 0.91 0.98 − 0.24 0.021 0.035*
 Fetal liver-to-body weight ratio 0.14 0.17 0.40 − 0.21 0.040 0.050
 Fetal brain-to-liver weight ratio − 0.17 0.09 0.40 0.09 0.36 0.36
Females only
 Fetal body weight 0.27 0.011 0.011* 0.75 < 0.001 < 0.001*
 Fetal brain-to-body weight ratio − 0.35 < 0.001 0.002* − 0.26 0.012 0.027*
 Fetal heart-to-body weight ratio − 0.31 0.004 0.006* 0.05 0.62 0.62
 Fetal liver-to-body weight ratio 0.28 0.007 0.009* − 0.25 0.016 0.027*
 Fetal brain-to-liver weight ratio − 0.39 < 0.001 0.001* 0.14 0.19 0.24
  1. Litters from all 4 treatments were combined and included in the analyses. The sample sizes were n = 9 litters for NP-MD-8 and NP-MD-13 groups; n = 8 litters for NP-Alc-8 group; n = 10 litters for NP-Alc-13 group. P values before and after multiple testing adjustment using Benjamini-Hochberg method are presented
  2. *Statistical significance at P < 0.05