An interaction between fetal sex and placental weight and efficiency predicts intrauterine growth in response to maternal protein insufficiency and gestational exposure window in a mouse model of FASD

Table 4 Correlation of the anthropometric measurements of the fetuses from dams in Groups 1 and 2 with their placental weight and efficiency

	Correlation with placental weight			Correlation with placental efficiency
	R	P_unadjusted	P_BH-adjusted	R	P_unadjusted	P_BH-adjusted
Males only
Fetal body weight	0.12	0.24	0.40	0.70	< 0.001	< 0.001*
Fetal brain-to-body weight ratio	0.003	0.98	0.98	− 0.43	< 0.001	< 0.001*
Fetal heart-to-body weight ratio	− 0.01	0.91	0.98	− 0.24	0.021	0.035*
Fetal liver-to-body weight ratio	0.14	0.17	0.40	− 0.21	0.040	0.050
Fetal brain-to-liver weight ratio	− 0.17	0.09	0.40	0.09	0.36	0.36
Females only
Fetal body weight	0.27	0.011	0.011*	0.75	< 0.001	< 0.001*
Fetal brain-to-body weight ratio	− 0.35	< 0.001	0.002*	− 0.26	0.012	0.027*
Fetal heart-to-body weight ratio	− 0.31	0.004	0.006*	0.05	0.62	0.62
Fetal liver-to-body weight ratio	0.28	0.007	0.009*	− 0.25	0.016	0.027*
Fetal brain-to-liver weight ratio	− 0.39	< 0.001	0.001*	0.14	0.19	0.24

Litters from all 4 treatments were combined and included in the analyses. The sample sizes were n = 9 litters for NP-MD-8 and NP-MD-13 groups; n = 8 litters for NP-Alc-8 group; n = 10 litters for NP-Alc-13 group. P values before and after multiple testing adjustment using Benjamini-Hochberg method are presented
*Statistical significance at P < 0.05

ISSN: 2042-6410