An interaction between fetal sex and placental weight and efficiency predicts intrauterine growth in response to maternal protein insufficiency and gestational exposure window in a mouse model of FASD

Table 2 Correlation of the anthropometric measurements of the fetuses from dams in Group 1 with their placental weight and efficiency

	Correlation with placental weight			Correlation with placental efficiency
	R	P_unadjusted	P_BH-adjusted	R	P_unadjusted	P_BH-adjusted
Males only
Fetal body weight	− 0.001	0.99	0.99	0.82	< 0.001	< 0.001*
Fetal brain-to-body weight ratio	0.15	0.38	0.63	− 0.67	< 0.001	< 0.001*
Fetal heart-to-body weight ratio	− 0.04	0.81	0.99	− 0.17	0.31	0.52
Fetal liver-to-body weight ratio	0.26	0.11	0.35	− 0.07	0.68	0.76
Fetal brain-to-liver weight ratio	− 0.24	0.14	0.35	− 0.05	0.76	0.76
Females only
Fetal body weight	0.48	< 0.001	0.001*	0.55	< 0.001	< 0.001*
Fetal brain-to-body weight ratio	− 0.53	< 0.001	< 0.001*	− 0.16	0.28	0.70
Fetal heart-to-body weight ratio	− 0.42	0.003	0.003*	0.04	0.78	0.84
Fetal liver-to-body weight ratio	0.41	0.004	0.004*	− 0.05	0.72	0.84
Fetal brain-to-liver weight ratio	− 0.48	< 0.001	0.001*	0.03	0.84	0.84

Litters from both treatments were combined and included in the analyses. The sample sizes were n = 9 litters for NP-MD-8 group; n = 8 litters for NP-Alc-8 group. P values before and after multiple testing adjustment using Benjamini-Hochberg method are presented
*Statistical significance at P < 0.05

ISSN: 2042-6410