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Table 3 The relationship between the degree of skewed XCI and clinical symptoms in MDD

From: A new sex-specific underlying mechanism for female schizophrenia: accelerated skewed X chromosome inactivation

MDD patient Patient age (years) Age of onset (years) Disease duration (months) HAMD Medicine (mg/day)
Total patient Coefficient 0.123 −0.007 −0.167 0.138 −0.16
  Significance 0.451 0.966 0.323 0.415 0.33
Adult patient Coefficient −0.165 −0.029 −0.186 0.41 0.109
  Significant 0.462 0.896 0.408 0.058 0.688
Elderly patient Coefficient −0.147 −0.235 −0.385 −0.086 −0.321
  Significance 0.586 0.4 0.157 0.759 0.145
  1. The relationship between degree of skewed XCI and clinical indicators analyzed by Spearman's correlation and Spearman's correlation was significant at p < 0.025 for age group of MDD patients.
  2. †Positive symptoms in the PANSS
  3. §Negative symptoms in the PANSS