Fig. 1

The horizontal lines represent the median, and significant differences are highlighted (Mann-Whitney U test). a Higher frequency of severe XCI skewing in schizophrenia patients. The results of female healthy controls (CNTLs) (n = 80), SCZ patients (n = 101), and MDD patients (n = 38) are shown. CNTL vs SCZ p = 0.003, CNTL vs MDD p = 0.363. b Higher frequency of severe XCI skewing in patients with severe symptoms of schizophrenia. The results of female healthy controls (CNTLs) (n = 80), SCZ: PANSS score ≥ 90 (n = 35), and SCZ: PANSS score < 90 (n = 64) are shown. CNTL vs SCZ: PANSS score ≥ 90 p = 0.004, CNTL vs SCZ: PANSS score < 90 p = 0.063 (a). b The horizontal lines represent the median, and statistical differences are highlighted (Mann-Whitney U test), p < 0.05