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Fig. 2 | Biology of Sex Differences

Fig. 2

From: Reference genome and transcriptome informed by the sex chromosome complement of the sample increase ability to detect sex differences in gene expression from RNA-Seq data

Fig. 2

Genetic sex of RNA-Seq samples. We investigated the gene expression, log2(CPM + 0.25/L), of XY homologous genes (DDX3X/Y, PCDH11X/Y, USP9X/Y, ZFX/Y, UTX/Y); XIST; and SRY in all samples from all tissues analyzed here from genetic males (blue squares) and genetic females (orange circles) a when aligned to a default reference genome and b when aligned to a sex chromosome complement informed reference genome, using HISAT as the read aligner

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