Fig. 5
From: Unfractionated heparin displaces sFlt-1 from the placental extracellular matrix
Heparin alters maternal blood pressure and offspring weight. Mean arterial pressure of pregnant Sprague Dawley rats infused with either unfractionated heparin (100 U/kg/day) or saline as a control, measured in conscious animals on gestational day 19 via indwelling carotid catheter (a). Average pup weight on gestational day 19 (b). Average placental mass on gestational day 19 (c). N = 9–10 per group. Statistical analysis performed using unpaired Student’s t test. Significance is designated by a bar connecting groups (*p < 0.05, **p < 0.01, ***p < 0.001)