Fig. 4
From: Unfractionated heparin displaces sFlt-1 from the placental extracellular matrix
Heparin alters sFlt-1 and VEGF localization. Placental sFlt-1 protein levels in pregnant Sprague Dawley rats infused with either unfractionated heparin (100 U/kg/day) or saline as a control, as measured by ELISA (a). VEGF protein levels in the placenta (b) and plasma (c), as measured by ELISA. Placental measurements expressed as pg of sFlt-1 or VEGF per milligram of placental protein. N = 9–10 per group. Statistical analysis performed using unpaired Student’s t test. Significance is designated by a bar connecting groups (*p < 0.05, **p < 0.01, ***p < 0.001)