- This table summarizes the outcomes of androgens’ modifications (removal by GDX or supplementation after GDX) on the MCAO model of stroke in young (< 6 months) versus old (12+ mo) rodents. Positive effects are indicated in green and negative effects are in red. GDX: gonadectomy; DHT: 5α-dihydrotestosterone; T: testosterone; MCAO: middle cerebral artery occlusion