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Table 6 Cluster membership in relation to cancer incidence in Iranian population in the Tehran Lipid and Glucose Study (1999–2014)

From: Sex-specific clustering of metabolic risk factors and cancer risk: a longitudinal study in Iran

 Model 1aModel 2b
HR(95% CI)P valueHR(95% CI)P value
Cluster 5ReferenceReference
Cluster 15.38(1.89–15.33)0.0022.56(0.89–7.39)0.080
Cluster 25.17(1.73–15.49)0.0032.65(0.87–8.03)0.083
Cluster 37.75(2.73–22.01)0.0033.56(1.23–10.28)0.018
Cluster 44.76(1.66–13.61)0.0012.46(0.85–7.11)0.096
Cluster 62.60(0.78–8.63)0.1183.05(0.91–10.14)0.068
Cluster 72.58(0.87–7.65)0.0852.23(0.75–6.62)0.146
Cluster 2ReferenceReference
Cluster 12.92(1.28–6.63)0.0102.23(0.97–5.13)0.057
Cluster 32.32(0.98–5.49)0.0541.78(0.75–4.25)0.190
Cluster 42.36(0.85–6.51)0.0961.54(0.55–4.33)0.404
Cluster 52.98(1.30–6.86)0.0091.53(0.64–3.64)0.330
Cluster 65.78(2.38–14.07)<0.0013.63(1.46–8.99)0.005
Cluster 72.42(1.04–5.61)0.0391.20(0.49–2.88)0.683
  1. aModel was unadjusted
  2. bModel was adjusted for age, smoking status, and educational and physical activity levels
  3. In the Cox regression models, cluster 5 and cluster 2 in men and women, respectively, with the lowest incidence rates of cancer (Tables 2 and 3) were considered as reference groups
  4. CI confidence interval, HR hazard ratio