Fig. 4

Module enrichment plot for PTSD-relevant modules identified in network analysis of cell-adjusted amygdalar expression levels (both sexes). Module M2 (bottom row) consists of 59 genes and is associated with upregulation in MBR and relative downregulation in CON, in both sexes. Module M3 (top row) consists of 55 genes and is weakly associated with downregulation in EBR groups of both sexes and upregulation in the female MBR group. The size and intensity of the circles correspond to the normalized enrichment score (NES) for the module in each class (normalized by the number of genes in the module)