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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Obesity: sex and sympathetics

Fig. 3

Obesity alters the sympathoexcitatory response to insulin in a sexually dimorphic way. Intracerebroventricular (icv) insulin increases lumbar sympathetic nerve activity (LSNA) similarly in lean [control diet (CON) or resistant to obesity development when consuming a high fat diet (OR)] males and females throughout the reproductive cycle. However, while obesity (obesity prone; OP) markedly amplifies the sympathoexcitatory response to icv insulin in males, in females, insulin’s action is abolished. Data adapted from [84]

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