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Fig. 3 | Biology of Sex Differences

Fig. 3

From: The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats

Fig. 3

Chronic infusion of AT1-AA into pregnant rats induced impaired CBF autoregulation. a Changes in CBF were plotted against mean arterial pressure in vehicle—(n = 3) or AT1-AA—(n = 4) infused rats. b Autoregulatory index was calculated for each pressure step and plotted against changes in MAP. Dashed horizontal line (AI = 1) corresponds to the complete loss of autoregulation. Data represent mean ± SEM. *p < 0.05 compared with vehicle. #p < 0.05 AT1-AA at 190 mmHg vs AT1-AA at 100 mmHg. Statistics were calculated using two-way repeated measures ANOVA

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