From: Sex differences in clinical presentation of systemic lupus erythematosus
Women % (frequency) | Men % (frequency) | p value | |
---|---|---|---|
I. Malar rash | 55.8% (592/1060) | 39.2% (65/166) | < 0.0001 |
II. Discoid rash | 24% (255/1060) | 18.7% (31/166) | 0.13 |
III. Photosensitivity | 66.7% (707/1060) | 43.4% (72/166) | < 0.0001 |
IV. Oral ulcer | 24.7% (262/1060) | 15.7% (26/166) | 0.01 |
V. Arthritis | 79.2% (840/1060) | 69.9% (116/166) | 0.007 |
VI. Serositis | 41.1% (436/1060) | 56% (93/166) | 0.0003 |
Pleuritis | 36.2% (302/833) | 47.1% (57/121) | 0.02 |
Pericarditis | 16.6% (138/833) | 27.3% (33/121) | 0.004 |
VII. Renal disorder | 29.9% (317/1060) | 54.2% (90/166) | < 0.0001 |
Proteinuria | 22.5% (88/391) | 47.2% (25/53) | 0.0001 |
Cellular casts | 16.1% (63/390) | 32.1% (17/53) | 0.005 |
VIII. Neurological disorder | 9.1% (97/1060) | 11.4% (19/166) | 0.35 |
Seizures | 7.2% (61/847) | 10.2% (13/127) | 0.23 |
Psychosis | 1.7% (14/847) | 3.1% (4/127) | 0.24 |
IX. Hematologic disorder | 61.5% (652/1060) | 60.2% (100/166) | 0.76 |
Hemolytic anemia | 7.2% (61/846) | 5.5% (7/127) | 0.48 |
Leukopenia | 42.7% (362/847) | 40.2% (51/127) | 0.58 |
Lymphopenia | 35.6% (301/846) | 32.3% (41/127) | 0.47 |
Thrombocytopenia | 17.9% (152/847) | 15.7% (20/127) | 0.51 |
X. Immunologic disorder | 65.8% (698/1060) | 74.1% (123/166) | 0.04 |
Anti-dsDNA | 59.5% (504/847) | 66.1% (84/127) | 0.15 |
Anti-Sm | 14% (118/845) | 15% (19/127) | 0.76 |
XI. ANA | 98.3% (1042/1060) | 98.2% (163/166) | 0.92 |
Number of fulfilled classification criteria (mean ± SD) | 5.6 ± 1.5 | 5.4 ± 1.4 | 0.18 |