Skip to main content
Fig. 1 | Biology of Sex Differences

Fig. 1

From: Statistical methods for testing X chromosome variant associations: application to sex-specific characteristics of bipolar disorder

Fig. 1

Association of X chromosome variants with BD. Top row denotes results from XCI-informed approach. Bottom row denotes results from XCI-robust approach. Green line denotes the study-wide significance threshold of 3.36 × 10−6. Domains as shown in the colored bars beneath the Manhattan plots for XCI-informed approach denote whether SNPs fall into regions experiencing (red) or escaping (blue) from X chromosome inactivation. Grey denotes regions for which a domain (subject or escaping) could not be assigned based on the paper by Balaton et al. [31]. SNPs are colored by the chosen XCI status used in the meta-analysis

Back to article page
\