Fig. 3
From: Cardiac hypertrophy with obesity is augmented after pregnancy in C57BL/6 mice
High-fat-fed postpartum mice exhibit increased left ventricular mass with enlargement of the left ventricular chamber. a Left ventricular (LV) mass. b LV posterior wall diameter (LVPWd). c LV end-diastolic diameter (LVEDd) in low-fat (LF)– and high-fat (HF)–fed nulliparous (NP) and postpartum (P) mice after 20 weeks of diet feeding. HF feeding increases LVPWd in the absence of LV chamber enlargement in NP mice. HF-fed postpartum mice have significantly increased LV mass accompanied by LV chamber dilation. Data are mean + SEM from n = 9–11 mice per group. *P < 0.01 compared with LF within group using 2-way ANOVA followed by Holm-Sidak pairwise analysis; #P < 0.05 compared with NP within diet group using 2-way ANOVA followed by Holm-Sidak pairwise analysis