|
Variables
|
All patients
|
Women
|
Men
| |
|---|
|
n = 285
|
n = 124
|
n = 161
|
p valuea
|
|---|
|
Age (years)
|
42 (32, 51; 18–59)
|
41 (30, 50()
|
43 (32, 52)
|
0.10
|
|
Diabetes duration (years)
|
20 (11, 30; 1–55)
|
19 (11, 29)
|
21 (11, 32)
|
0.27
|
|
Gal3BP b (mg/l)
|
2.3 (1.8, 3.1; 0.8–8.9)
|
2.6 (1.9, 3.6)
|
2.1 (1.6, 2.8)
|
< 0.001
|
|
sCD163 (mg/l) c
|
0.4 (0.3, 0.5; 0.2–1.9)
|
0.4 (0.3, 0.6)
|
0.4 (0.3, 0.5)
|
0.78
|
|
Galectin-3 (μg/l)
|
0.9 (0.6–1.7; 0.001–100)
|
0.9 (0.5, 1.4)
|
0.9 (0.6, 2.0)
|
0.15
|
|
HbA1c
|
|
mmol/mol
|
63 (54, 71; 25–110)
|
64 (54, 72)
|
63 (54, 69)
|
0.33
|
|
%
|
7.9 (7.1, 8.6; 4.4–12.2)
|
8.0 (7.1, 8.7)
|
7.9 (7.1, 8.5)
|
|
Total cholesterol (mmol/l)
|
4.6 (4.1, 5.1; 2.1–10.9)
|
4.6 (4.1, 5.4)
|
4.5 (4.0, 5.1)
|
0.13
|
|
Triglycerides (mmol/l)
|
0.9 (0.7, 1.3; 0.1–5.9)
|
0.8 (0.6, 1.3)
|
0.9 (0.7, 1.3)
|
0.32
|
|
LDL-cholesterol (mmol/l)
|
2.8 (2.4, 3.3; 0.6–8.3)
|
2.8 (2.4, 3.4)
|
2.8 (2.4, 3.3)
|
0.79
|
|
HDL-cholesterol (mmol/l)
|
1.5 (1.3, 1.8; 0.3–2.7)
|
1.6 (1.4, 1.9)
|
1.4 (1.2, 1.7)
|
0.003
|
|
Creatinine (μmol/l) d
|
70 (62, 182; 28–182)
|
62 (54, 70)
|
74 (68, 82)
|
< 0.001
|
|
Abdominal obesity e
|
47 (17)
|
34 (28)
|
13 (8)
|
< 0.001f
|
|
General obesity g
|
34 (12)
|
22 (18)
|
12 (8)
|
0.009 f
|
|
Systolic BP (mmHg)
|
20 (110, 130; 90–160)
|
120 (110, 130)
|
125 (120, 130)
|
< 0.001
|
|
Diastolic BP (mmHg)
|
70 (70, 76; 55–100)
|
70 (65, 75)
|
70 (70, 80)
|
< 0.001
|
|
Smoking h
|
27 (10)
|
10 (9)
|
17 (11)
|
0.55 f
|
|
Physical inactivity i
|
29 (11)
|
12 (10)
|
17 (11)
|
> 0.99 f
|
|
Depression
|
30 (10)
|
14 (11)
|
16 (10)
|
0.85 f
|
|
Cardiovascular complications
|
10 (4)
|
4 (3)
|
6 (4)
|
> 0.99 f
|
|
Diabetes retinopathy j
|
205 (72)
|
88 (72)
|
117 (73)
|
0.79 f
|
|
Foot complications k
|
47 (17)
|
13 (11)
|
34 (22)
|
0.023 f
|
|
Antidepressants
|
23 (8)
|
12 (10)
|
11 (7)
|
0.39 f
|
|
Antihypertensive drugs
|
96 (34)
|
35 (28)
|
61 (38)
|
0.10 f
|
|
Lipid lowering drugs
|
133 (47)
|
55 (44)
|
78 (48)
|
0.55 f
|
- a Mann-Whitney U test unless otherwise indicated. b galectin-3 binding protein. f Fisher’s Exact test. Missing values (N) (all/women/men): c 1/1/0; d 13/6/7; e 6/3/3; g 2/2/0; h, i 17/9/8; j 2/1/1; k 12/7/5
