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Fig. 1 | Biology of Sex Differences

Fig. 1

From: The influence of biological sex and sex hormones on bile acid synthesis and cholesterol homeostasis

Fig. 1

Schematic overview of bile acid synthesis from cholesterol in the liver. Enzymes in white boxes indicate endoplasmic reticulum localization, while gray boxes indicate cytosolic localization. Black boxes indicate mitochondrial membrane localization. Products of enzymatic reactions are listed below each cytochrome P450. Classical pathway enzymes are linked with solid arrows, and alternative pathway enzymes are connected with dashed arrows [16]. Inset: structure of cholesterol with numbered carbons. CA cholic acid, CDCA chenodeoxycholic acid. Adapted from Fuchs, 2003

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