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Table 2 MSC viability, function, and immunocytochemistry of fat tissue in women with normotensive vs. preeclamptic pregnancies

From: Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia

Variable Normotensive/preeclamptic samples Normotensive Preeclampsia p
Live cells, % 12/10 92.47 (91.53–93.41) 88.50 (85.12–91.86) 0.012
Dead cells, % 12/10 4.21 (3.57–4.86) 7.16 (4.41–9.91) 0.019
Proliferation (OD)x 10/7 0.80 (0.62–0.99) 0.44 (0.32–0.57) 0.005
Migration (OD)x 10/7 1.30 (0.99–1.61) 1.88 (1.42–2.33) 0.023
DHE 12/9 0.287 (0.241–0.334) 0.352 (0.284–0.419) 0.084
TNF-alpha 12/9 0.090 (0.058–0.122) 0.284 (0.210–0.358) < 0.001
MCP-1 12/9 0.058 (0.041–0.075) 0.085 (0.069–0.101) 0.024
  1. Results are expressed as mean (95% CI)
  2. DHE dihydroethidium, TNF-alpha tumor necrosis factor-alpha, MCP-1 monocyte chemoattractant protein-1, OD optical density units
  3. xProliferation and migration measured at 490 and 560 nm wavelengths, respectively
  4. Expressed as the percent of the field-of-view staining (average of 4–6 fields)