From: Adipocyte deficiency of ACE2 increases systolic blood pressures of obese female C57BL/6 mice
Parameter | Baseline | 12 weeks of estradiol |
---|---|---|
BMI (m/kg2) | 37.5 ± 3.4 | 38.1 ± 3.4 |
Plasma renin activity (ng/mL*h) | 0.85 ± 0.25 | 0.76 ± 0.25 |
Plasma angiotensinogen (μg/mL) | 17.0 ± 3.9 | 20.8 ± 5.0 |
Plasma AngII (pg/mL) | 42.3 ± 9.0 | 40.8 ± 14.6 |
Plasma Ang-(1-7) (ng/mL) | 0.36 ± 0.05 | 0.42 ± 0.02 |
Ratio of Ang-(1-7)/AngII (pg/mL) | 5.53 ± 1.74 | 14.13 ± 3.73 |