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Table 3 Characteristics of obese, transgendered women at baseline, and 12 weeks following oral estradiol therapy.

From: Adipocyte deficiency of ACE2 increases systolic blood pressures of obese female C57BL/6 mice

Parameter Baseline 12 weeks of estradiol
BMI (m/kg2) 37.5 ± 3.4 38.1 ± 3.4
Plasma renin activity (ng/mL*h) 0.85 ± 0.25 0.76 ± 0.25
Plasma angiotensinogen (μg/mL) 17.0 ± 3.9 20.8 ± 5.0
Plasma AngII (pg/mL) 42.3 ± 9.0 40.8 ± 14.6
Plasma Ang-(1-7) (ng/mL) 0.36 ± 0.05 0.42 ± 0.02
Ratio of Ang-(1-7)/AngII (pg/mL) 5.53 ± 1.74 14.13 ± 3.73