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Table 2 Telemetry parameters of male mice

From: Adipocyte deficiency of ACE2 increases systolic blood pressures of obese female C57BL/6 mice

 

Ace2 fl/y

Ace2 Adipo

LF

HF

LF

HF

24 h

 MAP (mmHg)

112.5 ± 0.8

117.7 ± 0.7*

114.1 ± 0.9

115.3 ± 1.2

 Heart rate (bpm)

556.7 ± 6.7

582.2 ± 7.5*

559.7 ± 6.5

581.1 ± 14.2*

 Activity (counts/min)

5.9 ± 0.7

5.0 ± 0.5

5.6 ± 0.8

5.5 ± 0.7

 PP (mmHg)

31.3 ± 2.1

38.2 ± 1.0

33.8 ± 2.0

33.18 ± 2.8

Light

 SBP (mmHg)

120.9 ± 1.3

130.0 ± 1.6*

123.88 ± 1.6

128.8 ± 2.5

 DBP (mmHg)

91.6 ± 0.6

93.3 ± 1.1

91.9 ± 1.2

94.6 ± 1.6

 MAP (mmHg)

106.3 ± 0.4

112.2 ± 1.2*

108.1 ± 0.8

110.9 ± 1.5

 Heart rate (bpm)

524.3 ± 5.2

555.3 ± 10.1*

534.6 ± 11.1

561.4 ± 13.0

 Activity (counts/min)

3.0 ± 0.3

3.3 ± 0.5

3.0 ± 0.4

3.5 ± 0.2

 PP (mmHg)

29.2 ± 1.9

35.6 ± 0.8

31.9 ± 1.9

32.3 ± 2.5

Dark

 SBP (mmHg)

139.0 ± 1.3

142.1 ± 2.3

140.5 ± 2.5

134.5 ± 3.7

 DBP (mmHg)

105.3 ± 2.1

104.3 ± 1.2

104.1 ± 1.0

102.5 ± 1.6

 MAP (mmHg)

122.3 ± 1.3

125.4 ± 1.7

122.4 ± 1.4

120.4 ± 2.2

 Heart rate (bpm)

598.6 ± 10.6

621.3 ± 7.7

595.3 ± 3.7

614.9 ± 15.0

 Activity (counts/min)

10.8 ± 1.1

7.3 ± 0.7

9.2 ± 1.4

7.4 ± 1.7

 PP (mmHg)

33.7 ± 2.5

40.9 ± 1.4

36.4 ± 2.2

35.1 ± 3.0

  1. PP pulse pressure, SBP systolic blood pressure, DBP diastolic blood pressure, MAP mean arterial pressure
  2. Data are mean ± SEM (n = 4–5 mice/diet/genotype)
  3. *p < 0.05 compared to LF within genotype following pairwise statistical analysis
  4. #p < 0.05 compared to Ace2fl/y within the diet group following pairwise statistical analysis