Skip to main content

Table 1 Telemetry parameters of female mice

From: Adipocyte deficiency of ACE2 increases systolic blood pressures of obese female C57BL/6 mice

  Ace2 fl/fl Ace2 Adipo
LF HF LF HF
24 h
 MAP (mmHg) 105.3 ± 1.1 112.4 ± 2.1* 106.1 ± 0.7 117.7 ± 2.1, #
 Heart rate (bpm) 584 ± 8 617 ± 9* 563 ± 4# 622 ± 7*
 Activity (counts/min) 12.8 ± 1.4 6.5 ± 0.6* 9.9 ± 1.5 6.4 ± 0.8*
 PP (mmHg) 32.2 ± 1.2 30.8 ± 1.4 30.7 ± 1.5 32.0 ± 1.5
Light
 SBP (mmHg) 115.3 ± 1.1 122.3 ± 1.9* 114.9 ± 1.3 127.8 ± 2.5*
 DBP (mmHg) 84.5 ± 0.8 92.7 ± 2.4* 85.2 ± 1.3 97.1 ± 1.0*
 MAP (mmHg) 100.7 ± 0.7 100.8 ± 2.0* 100.8 ± 1.2 113.3 ± 2.1*, #
 Heart rate (bpm) 576.6 ± 8.2 606.8 ± 9.3* 549.0 ± 4.5 610.8 ± 9.5*
 Activity (counts/min) 7.1 ± 1.0 4.9 ± 0.4* 5.8 ± 0.7 4.3 ± 0.7
 PP (mmHg) 30.8 ± 1.2 29.6 ± 1.3 29.7 ± 1.3 30.6 ± 1.3
Dark
 SBP (mmHg) 128.3 ± 0.4 134.3 ± 1.9 129.0 ± 1.7 139.7 ± 2.4*
 DBP (mmHg) 94.0 ± 1.6 101.4 ± 2.8* 96.7 ± 0.6 105.3 ± 1.7*
 MAP (mmHg) 111.8 ± 1.6 118.5 ± 2.2* 113.5 ± 0.9 123.6 ± 2.0*
 Heart rate (bpm) 596.4 ± 8.1 634.0 ± 8.4* 578.9 ± 6.8 635.0 ± 7.0*
 Activity (counts/min) 20.0 ± 1.8 8.9 ± 0.8* 15.1 ± 2.5 9.4 ± 1.2*
 PP (mmHg) 34.4 ± 1.3 32.9 ± 1.5 32.2 ± 1.7 33.8 ± 1.4
  1. PP pulse pressure, SBP systolic blood pressure, DBP diastolic blood pressure, MAP mean arterial pressure
  2. Data are mean ± SEM (n = 4–5 mice/diet/genotype)
  3. *p < 0.05 compared to LF within genotype following pairwise statistical analysis
  4. #p < 0.05 compared to Ace2fl/fl within the diet group following pairwise statistical analysis