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Table 1 Telemetry parameters of female mice

From: Adipocyte deficiency of ACE2 increases systolic blood pressures of obese female C57BL/6 mice

 

Ace2 fl/fl

Ace2 Adipo

LF

HF

LF

HF

24 h

 MAP (mmHg)

105.3 ± 1.1

112.4 ± 2.1*

106.1 ± 0.7

117.7 ± 2.1, #

 Heart rate (bpm)

584 ± 8

617 ± 9*

563 ± 4#

622 ± 7*

 Activity (counts/min)

12.8 ± 1.4

6.5 ± 0.6*

9.9 ± 1.5

6.4 ± 0.8*

 PP (mmHg)

32.2 ± 1.2

30.8 ± 1.4

30.7 ± 1.5

32.0 ± 1.5

Light

 SBP (mmHg)

115.3 ± 1.1

122.3 ± 1.9*

114.9 ± 1.3

127.8 ± 2.5*

 DBP (mmHg)

84.5 ± 0.8

92.7 ± 2.4*

85.2 ± 1.3

97.1 ± 1.0*

 MAP (mmHg)

100.7 ± 0.7

100.8 ± 2.0*

100.8 ± 1.2

113.3 ± 2.1*, #

 Heart rate (bpm)

576.6 ± 8.2

606.8 ± 9.3*

549.0 ± 4.5

610.8 ± 9.5*

 Activity (counts/min)

7.1 ± 1.0

4.9 ± 0.4*

5.8 ± 0.7

4.3 ± 0.7

 PP (mmHg)

30.8 ± 1.2

29.6 ± 1.3

29.7 ± 1.3

30.6 ± 1.3

Dark

 SBP (mmHg)

128.3 ± 0.4

134.3 ± 1.9

129.0 ± 1.7

139.7 ± 2.4*

 DBP (mmHg)

94.0 ± 1.6

101.4 ± 2.8*

96.7 ± 0.6

105.3 ± 1.7*

 MAP (mmHg)

111.8 ± 1.6

118.5 ± 2.2*

113.5 ± 0.9

123.6 ± 2.0*

 Heart rate (bpm)

596.4 ± 8.1

634.0 ± 8.4*

578.9 ± 6.8

635.0 ± 7.0*

 Activity (counts/min)

20.0 ± 1.8

8.9 ± 0.8*

15.1 ± 2.5

9.4 ± 1.2*

 PP (mmHg)

34.4 ± 1.3

32.9 ± 1.5

32.2 ± 1.7

33.8 ± 1.4

  1. PP pulse pressure, SBP systolic blood pressure, DBP diastolic blood pressure, MAP mean arterial pressure
  2. Data are mean ± SEM (n = 4–5 mice/diet/genotype)
  3. *p < 0.05 compared to LF within genotype following pairwise statistical analysis
  4. #p < 0.05 compared to Ace2fl/fl within the diet group following pairwise statistical analysis