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Fig. 2 | Biology of Sex Differences

Fig. 2

From: Adipocyte deficiency of ACE2 increases systolic blood pressures of obese female C57BL/6 mice

Fig. 2

Deficiency of ACE2 in adipocytes has no effect on the development of obesity in male or female mice. Body weights (weekly) of female Ace2fl/fl (a) or male Ace2fl/y (b) and Ace2Adipo mice fed a low fat (LF) or high fat (HF) diet. Lean mass (c) and fat mass (d) (as % body weight) of female or male mice from each genotype fed the LF or HF diet. Data are mean + SEM from n = 6–13 mice/genotype/diet. *p < 0.05 compared to LF within sex using two-way ANOVA followed by Holm-Sidak pairwise analysis; @p < 0.01 compared to female within diet group using two-way ANOVA followed by Holm-Sidak pairwise analysis

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