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Table 3 Male-biased expression of transcription and epigenetic factors

From: The developmental origins of sex-biased expression in cardiac development

Transcription factors and epigenetic and remodelling enzymes ES CP 8.5 9.5 10.5 p1 Adult Chr Name
Egr4 XY        6 Early growth response 4
Cdx1 XY        18 Caudal type homeobox 1
E2f7 XY        10 E2F transcription factor 7
Eomes XY        9 Eomesodermin
Evx1 XY        6 Even-skipped homeobox 1
Foxi3 XY        6 Forkhead box I3
Foxp4 XY        17 Forkhead box P4
Insm1 XY        2 Insulinoma-associated 1
Lin28a XY        4 Lin-28 homolog A (C. elegans)
Mesp1 XY        7 Mesoderm posterior 1
Mixl1 XY        1 Mix1 homeobox-like 1 (Xenopus laevis)
Nr6a1 XY        2 Nuclear receptor subfamily 5, group A, member 1
Pou2f3 XY        9 POU domain, class 2, transcription factor 3
Sox11 XY        12 SRY (sex determining region Y)-box 11
Sp5 XY        9 Per-hexamer repeat gene 4
Sp8 XY        12 Trans-acting transcription factor 8
T XY        17 Brachyury, T-box transcription factor T
Tcf7 XY        11 Transcription factor 7, T cell specific
Wiz XY        17 Widely-interspaced zinc finger motifs
Ybx2 XY        11 Y box protein 2
Zglp1 XY        9 Zinc finger, GATA-like protein 1
Dnmt3b XY        2 DNA methyltransferase 3B
Dnmt3l XY        10 DNA (cytosine-5-)-methyltransferase 3-like
Phc1 XY        6 Polyhomeotic 1
Plac8 XY        5 Placenta-specific 8
Tdrd5 XY        1 Tudor domain containing 5
Bahcc1 XY        11 BAH domain and coiled-coil containing 1
Kdm6c XY XY XY XY XY   XY Y Ubiq.transcribed tetratricopeptide repeat gene, Y chr
Bcl6b XY XY      nb 11 B cell CLL/lymphoma 6, member B
Irf8 XY XY      nb 8 Interferon regulatory factor 8
Arid1a XY XY       4 AT rich interactive domain 1A (SWI-like)
Lef1 XY   XY    XY XY 3 Lymphoid enhancer binding factor 1
Tbx20 XY XY    XY XY   9 T-box 20
Smarcd1 XY      XY   15 SWI/SNF related, matrix assoc., actin-dep. reg. of chromatin d1
Zbtb7a XY      XY   10 Zinc finger and BTB domain containing 7a
Hif3a XY XY     XY   7 hypoxia inducible factor 3, alpha subunit
Nfkb2 XY      XY XY 19 nuclear factor of κ light polypeptide enhancer B cells 2, p49/p100
Pbx2 XY      XY nb 17 Pre B cell leukemia homeobox 2
Prdm6 XY       XY 18 PR domain containing 6
Id2 XY       XY 12 Inhibitor of DNA binding 2
Dot1l XY      XY XX 10 DOT1-like, histone H3 methyltransferase (S. cerevisiae)
Zfp296 XY      XX   7 Zinc finger protein 296
Gata4 XY       nb 14 GATA binding protein 4
Mycn XY       nb 12 v-myc avian myelocytomatosis related og, neuroblastoma derived
Hdac5 XY       nb 11 Histone deacetylase 5
Nfxl1 XY       nb 5 Nuclear transcription factor, X-box binding-like 1
Pax6 nb XY       2 Paired box 6
Brd4 nb XY      nb 17 Bromodomain containing 4
Carhsp1 nb   XY    XY XY 16 Calcium regulated heat stable protein 1
Csde1 nb   XY XY   nb nb 3 Cold shock domain containing E1, RNA binding
Mef2d nb      XY   3 Myocyte enhancer factor 2D
Atf5 nb       XY 7 activating transcription factor 5
Bach2 nb       XY 4 BTB and CNC homology, basic leucine zipper transcription factor 2
Cdc5l nb       XY 17 Cell division cycle 5-like (S. pombe)
Crebzf nb       XY 7 CREB/ATF bZIP transcription factor
Gm13139 nb       XY 4 Zinc finger protein 991
Hmgb1 nb       XY 2 Predicted gene, 21596
Hmgb2 nb       XY 8 High mobility group box 2
Klf10 nb       XY 15 Kruppel-like factor 10
Nfic nb       XY 10 Nuclear factor I/C
Nfkb1 nb       XY 3 Nuclear factor of κ light polypeptide enhancer in B cells 1, p105
Pias2 nb       XY 18 Protein inhibitor of activated STAT 2
  1. ES embryonic stem cells; CP cardiac precursors; 8.5, 9.5, 10.5 days post coitum (dpc) embryonic hearts (single cell); p1 neonatal hearts; Chr chromosome; empty cells expression not detected; nb expressed but not biased
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