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Fig. 3 | Biology of Sex Differences

Fig. 3

From: The developmental origins of sex-biased expression in cardiac development

Fig. 3

Sex-biased chromatin modifications at regulatory sequences in ES cells. ChIP-Seq results on two XX (red, light pink, dark pink lines) and XY (blue, teal, and dark blue lines) ES cell lines for H3K27Ac, H3K27Me3, and H3K4Me1, respectively, are shown. IgG served as a control. NGS-plot was used to evaluate the enrichment of the histone modifications at transcriptional start sites and known enhancers. The plots depict the average profile of histone modifications at regions of interest, providing a quantitative view of the patterns for each ES cell line

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