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Table 1 Baseline characteristics of the study population

From: Sex-specific association of metabolic risk factors with brain ischemic lesions by severity and location

 

Overall (n = 5791)

Female (n = 2396)

Male (n = 3395)

p value

Age, year

48.8 (10.1)

49.2 (10.4)

48.6 (9.92)

0.024

BMI, kg/m2

24.0 (3.34)

22.7 (3.12)

25.0 (3.19)

< 0.001

SBP, mmHg

116 (14.7)

114 (15.6)

117 (13.9)

< 0.001

DBP, mmHg

78.6 (9.5)

76.1 (9.3)

80.4 (9.2)

< 0.001

Fasting glucose, mmol/L

5.16 (1.19)

5.02 (0.97)

5.26 (1.32)

< 0.001

HbA1C, %

5.54 (0.74)

5.45 (0.62)

5.61 (0.82)

< 0.001

TG, mmol/L

1.77 (1.38)

1.35 (0.96)

2.07 (1.55)

< 0.001

TC, mmol/L

5.06 (0.99)

5.02 (0.96)

5.09 (1.01)

0.004

HDL-C, mmol/L

1.33 (0.373)

1.52 (0.376)

1.20 (0.306)

< 0.001

N-HDL-C, mmol/L

3.73 (1.01)

3.50 (0.96)

3.89 (1.02)

< 0.001

LDL-C, mmol/L

2.96 (0.875)

2.90 (0.862)

3.01 (0.882)

< 0.001

Lp(a), mg/L

114 [53.3, 234]

130 [67.0, 253]

103 [46.0, 219]

< 0.001

APOB, g/L

0.923 (0.224)

0.870 (0.216)

0.960 (0.222)

< 0.001

APOA-1, g/L

1.52 (0.269)

1.62 (0.268)

1.45 (0.247)

< 0.001

APOE, mg/L

45.7 (16.7)

44.3 (14.3)

46.6 (18.2)

0.002

ALT, U/L

20.0 [13.5, 31.1]

14.5 [10.8, 20.9]

25.1 [17.6, 37.5]

< 0.001

AST, U/L

21.0 [17.4, 26.0]

19.0 [16.0, 23.0]

22.5 [19.0, 28.0]

< 0.001

GGT, U/L

27.0 [17.0, 48.0]

17.3 [13.0, 24.6]

38.0 [25.0, 63.0]

< 0.001

UA, umol/L

339 (90.0)

273 (61.3)

386 (77.1)

< 0.001

BUN, mmol/L

4.93 (1.20)

4.65 (1.20)

5.13 (1.17)

< 0.001

Scr, umol/L

76.0 (16.3)

62.2 (9.43)

85.8 (12.7)

< 0.001

CRP, mg/L

0.99 [0.54, 1.89]

0.79 [0.45, 1.50]

1.12 [0.63, 2.18]

0.000

Hypertension, n (%)

1205 (20.8%)

383 (16.0%)

822 (24.2%)

< 0.001

Dyslipidemia, n (%)

2155 (37.2%)

521 (21.7%)

1634 (48.1%)

< 0.001

Pre-diabetes, n (%)

1483 (25.6%)

567 (23.7%)

916 (27.0%)

< 0.001

Diabetes, n (%)

299 (5.2%)

59 (2.5%)

240 (7.1%)

< 0.001

Mild to moderate fatty liver, n (%)

1275 (22.0%)

345 (14.4%)

930 (27.4%)

< 0.001

Severe fatty liver, n (%)

1200 (20.7%)

297 (12.4%)

903 (26.6%)

< 0.001

Overweight, n (%)

2194 (37.9%)

605 (25.3%)

1589 (46.8%)

< 0.001

Obese, n (%)

657 (11.3%)

139 (5.8%)

518 (15.3%)

< 0.001

Metabolic Syndrome, n (%)

1407 (24.3%)

358 (14.9%)

1049 (30.9%)

< 0.001

  1. Data presented as mean (SD) or median (IQR) and n (%)
  2. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, N-HDL-C non-high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Lp(a) lipoprotein a, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT gamma-glutamyl transferase, UA uric acid, BUN blood urea nitrogen, Scr serum creatinine, CRP C-reactive protein
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Biology of Sex Differences

ISSN: 2042-6410

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