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Table 2 Sex differences in metabolic effects of the RAS in clinical opulations

From: Sex differences in the metabolic effects of the renin-angiotensin system

RAS component Obesity Dyslipidemia Insulin sensitivity Glucose tolerance References
Angiotensinogen
 Males UNK UNK UNK [100]
 Females UNK [100,101,102]
Renin
 Males UNK [103]
 Females ↓, ↑ UNK [103]
Prorenin
 Males UNK UNK UNK UNK  
 Females UNK UNK UNK UNK  
Angiotensin II
 Males [104,105,106]
 Females [104, 107]
ACE
 Males - [108,109,110]
 Females - [101, 108, 110]
AT1 receptors
 Males - [103, 105, 110,111,112,113]
 Females - [103, 105, 110, 112, 113]
AT2 receptors
 Males UNK UNK UNK UNK  
 Females UNK [114, 115]
Angiotensin-(1-7)
 Males UNK UNK UNK UNK  
 Females UNK UNK UNK UNK  
ACE2
 Males UNK UNK UNK UNK  
 Females UNK UNK UNK UNK  
Mas receptors
 Males UNK UNK UNK [116]
 Females UNK UNK UNK [116]
Alamandine
 Males UNK UNK UNK UNK  
 Females UNK UNK UNK UNK  
  1. ACE angiotensin-converting enzyme, ACE2 angiotensin-converting enzyme 2, AT1 angiotensin II type 1, AT2 angiotensin II type 2, RAS renin-angiotensin system, ↑ increases, ↓ decreases, - neutral effects, UNK information currently unknown