Fig. 2

Nicotine enhances goal-tracking in male and female rats. Expression of goal-tracking behaviors over 29 days of training (left) and averaged across the last 10 days of training (right) in male and female rats exposed to nicotine or to saline. Data are expressed as mean ± SEM, and reflect separate measures of conditioned approach to the reward receptacle: Top latency to enter the receptacle; Middle receptacle elevation score per trial; Bottom probability of entering the receptacle during a trial. * Main effect of nicotine exposure, p < 0.05