Table 1 Patient data
From: Polypharmacy in patients with multiple sclerosis: a gender-specific analysis
Women, N (%) | Men, N (%) | p value | |||
|---|---|---|---|---|---|
N | 218 | 88 | |||
Sociodemographic data | |||||
Age (years) | 19–86R | 48.3 (13.7)a | 24–78R | 49.6 (11.4)a | 0.375t |
≤ 29 | 20 (9.2) | 3 (3.4) | |||
30–39 | 46 (21.1) | 18 (20.5) | |||
40–49 | 42 (19.3) | 22 (25.0) | |||
50–59 | 66 (30.3) | 30 (34.1) | |||
≥ 60 | 44 (20.2) | 15 (17.0) | |||
School years | 6–16R | 10b | 8–13R | 10b | 0.386U |
Educational level | 0.531Chi | ||||
No training | 5 (2.3) | 1 (1.1) | |||
Skilled worker | 151 (69.3) | 55 (62.5) | |||
Technical college | 13 (6.0) | 6 (6.8) | |||
University | 49 (22.5) | 26 (29.5) | |||
Employment status | 0.092Chi | ||||
In training | 5 (2.3) | 1 (1.1) | |||
Employed | 73 (33.5) | 42 (47.7) | |||
Unemployed | 8 (3.7) | 2 (2.3) | |||
Retiree | 125 (57.3) | 43 (48.9) | |||
Others | 7 (3.2) | 0 (0.0) | |||
Partnership | 0.888Fi | ||||
Yes | 159 (72.9) | 63 (71.6) | |||
No | 59 (27.1) | 25 (28.4) | |||
Place of residence | 0.125Chi | ||||
Rural community | 68 (31.2) | 17 (19.3) | |||
Provincial town | 42 (19.3) | 15 (17.0) | |||
Medium-sized town | 29 (13.3) | 14 (15.9) | |||
City | 79 (36.2) | 42 (47.7) | |||
Number of children | 0–4R | 1b | 0–4R | 1b | 0.088U |
0 | 56 (25.7) | 25 (28.4) | |||
1 | 57 (26.1) | 30 (34.1) | |||
≥ 2 | 105 (48.2) | 33 (37.5) | |||
Number of siblings | 0–13R | 1b | 0–7R | 1b | 0.649U |
0 | 27 (12.4) | 13 (14.8) | |||
1 | 105 (48.2) | 42 (47.7) | |||
≥ 2 | 86 (39.4) | 33 (37.5) | |||
Clinical data | |||||
EDSS | 1.0–9.0R | 3.5b | 1.0–9.0R | 3.5b | 0.471U |
Disease duration (years) | 0–50R | 11.0b | 0–41R | 11.5b | 0.872U |
0*–5 | 68 (31.2) | 20 (22.7) | |||
6–10 | 36 (16.5) | 21 (23.9) | |||
11–15 | 35 (16.1) | 19 (21.6) | |||
16–20 | 37 (17.0) | 15 (17.0) | |||
≥ 21 | 42 (19.3) | 13 (14.8) | |||
Disease course | 0.041 Chi | ||||
CIS/RRMS | 140 (64.2) | 52 (59.1) | |||
SPMS | 60 (27.5) | 20 (22.7) | |||
PPMS | 18 (8.3) | 16 (18.2) | |||
Comorbidities | 0.237Fi | ||||
Pw/oSI | 73 (33.5) | 36 (40.9) | |||
PwSI | 145 (66.5) | 52 (59.1) | |||
Patient care | 0.527Fi | ||||
Outpatients | 107 (49.1) | 39 (44.3) | |||
Inpatients | 111 (50.9) | 49 (55.7) | |||
Pharmacological data | |||||
Polypharmacy | 122 (56.0) | 51 (58.0) | 0.799Fi | ||
All medicationsc | 5.8 (3.7) | 5.3 (3.1) | 0.443U | ||
Long-term medicationsc | 4.6 (3.4) | 4.1 (2.8) | 0.353U | ||
PRN drugsc | 1.2 (1.4) | 1.2 (1.3) | 0.972U | ||
Prescription-only drugsc | 4.7 (3.4) | 4.2 (2.6) | 0.618U | ||
OTC drugsc | 1.2 (1.3) | 1.1 (1.2) | 0.730U | ||
DMDc | 1.0 (0.3) | 0.9 (0.3) | 0.437U | ||
Symptomatic drugsc | 1.9 (1.9) | 2.1 (1.9) | 0.212U | ||
Comorbidity drugsc | 3.0 (2.7) | 2.3 (2.1) | 0.021 U | ||