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Fig. 7 | Biology of Sex Differences

Fig. 7

From: Inflammatory responses to dietary and surgical weight loss in male and female mice

Fig. 7

VSG improves IWAT CD11c+ ATMs and DCs. Six-week-old C57Bl/6J males and females were fed HFD for 12 weeks. At that time, animals underwent sham surgery or vertical sleeve gastrectomy (VSG). Sham animals were either switched to chow or remained on HFD for an additional 8 weeks. At 26 weeks of age, animals were sacrificed and IWAT stromal vascular fraction (SVF) was isolated and flow cytometry used to quantitate a ATMs, b CD11c ATMs, c CD11c+ ATMs, and d dendritic cells (DC). e Myeloid leukocyte subtypes profiled in ovariectomized female mice. *p < 0.05, **p < 0.01, ****p < 0.001. N = 9–18

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