Fig. 3
From: Inflammatory responses to dietary and surgical weight loss in male and female mice
Male and female hematopoietic cells transplanted from weight loss animals are no longer primed to impair metabolism. ND, HFD, and WL animals were generated and at 26 weeks of age, bone marrow was injected into irradiated C57Bl6/j mice of the same sex. Six weeks following bone marrow transplantation, all mice were started on a 60% HFD. a Insulin tolerance tests (ITT) studies were performed in males at 14 weeks of HFD. GTT studies were performed at 12 weeks of HFD in b males and c females with calculated area under the curve (AUC). After 16 weeks of HFD, animal d weight and tissue, e GWAT, f IWAT, and g liver were measured. *p < 0.05. #p < 0.05, ##p < 0.01, ### p < 0.005, ####p < 0.001 for comparisons between sexes of the same diet group. N = 4–10 per group