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Table 3 Rates of change in cognitive test scores in men vs. women

From: Sex and genetic differences in postoperative cognitive dysfunction: a longitudinal cohort analysis

 

Non-surgical men (slope)

Non-surgical women (slope)

Surgical men (slope)

Surgical women (slope)

Surgical exposure main effect

(p value)

Sex effect—no surgical exposure

(p value)

Sex effect—surgical exposure (p value)

Global cognitive function tests

MMSE

− 0.02528

− 0.01907

− 0.03539

− 0.02704

< 0.001

0.13

0.33

CDR-SB

0.3568

0.2991

0.483

0.425

< 0.001

0.24

0.95

Memory-based tests

Logical Memory Delayed Recall

− 0.07798

− 0.08284

− 0.2623

− 0.2914

< 0.001

0.86

0.84

CERAD Delayed Word List

−0.03858

− 0.0445

0.05887

− 0.05463

< 0.001

0.35

0.13

Attention-based tests

Digit Symbol

− 0.8686

− 0.948

− 1.244

− 1.271

< 0.001

0.31

0.65

SDMT

− 1.312

− 0.8192

− 1.226

− 1.134

0.24

0.08

0.74

Executive function tests

Trails Making Test B

5.1

3.419

10.81

9.089

0.12

0.36

0.86

Animal Category Fluency

− 0.4655

− 0.3809

− 0.5711

− 0.5551

< 0.001

0.15

0.35