Fig. 5From: Sex-specific lipid molecular signatures in obesity-associated metabolic dysfunctions revealed by lipidomic characterization in ob/ob mouseSex differences in hepatic regulation of key genes of the FA and PL biosynthesis pathways. Graphical illustration of the transcriptional regulation of the a saturated, monounsaturated and polyunsaturated fatty acid biosynthesis pathways; b Phosphocholine/Lysophosphatidylcholine and Phosphoethanolamine/Lysophosphatidyl-ethanolamine synthesis pathways in F and M mouse liver. Blue denotes higher hepatic expression in male and pink in female mice; black shows no difference between sexes. Abbreviations: Elovl: fatty acid elongase, Scd: fatty acid desaturase, Ck: choline kinase, Ct: choline transferase, Ek: ethanolamine kinase, Et: ethanolamine transferase, Pemt: phosphatidylethanolamine N-methyltransferase and Lp-Pla2: Lipoprotein associated phospholipase A2Back to article page